Bilberry/Pine Bark (2008, 2010, 2015) & Glaucoma

Learn more about glaucoma .
2015
A discipline tested the effect of a append ( ProVens® ) containing extracts of nautical pine bark, green tea, and blueberry ( alike to bilberry ). These extracts contained antioxidant proanthocyanidins ( pine bark ), polyphenols ( greens tea ) and anthocyanins ( blueberry ). All three types of nutrients are amount the class of antioxidants called bioflavonoids comprised of the colorant material of different plant forms .
The patients received the supplement once a day. The dose was 50mg pine bark, 100mg green tea, and 3mg blueberry. The patients in the trial had either high intraocular imperativeness ( IOP ) ( 35 ) or open-angle glaucoma ( 11 – who had been treated with prostaglandin analogs.

IOP was measured by standard methods at the begin of the trial menstruation, after one month and after three months .
There was statistically significant decrease in IOP in the patients with high IOP ( from ave. 24.2mmHg to ave. 20.9mmHG ) within the three calendar month period. In the patients with open-angle glaucoma there was besides a reduction ( from ave. 18.4mmHG to ave 17.0mmHG ) within three months. No slope effects were reported for either group .
The researchers concluded that this addendum formulation could be an effective method acting to help control senior high school IOP .
Researchers : M. Karhanova, M. Eliasova, et al
ProVens® in the Therapy of Glaucoma and Ocular Hypertension, Ceska a Slovinska Oftalomogie, Winter, 2015 .
2010
An earlier report examined the effects of a formulation called Mirtogenol which combines french nautical pine bark and bilberry. The group studied consisted of 79 patients living with “ asymptomatic ocular high blood pressure ”. The participants were separated into three groups :

1. received 80 mg of Mitroselect bilberry extract and 40 mg of
   Pycnogenol daily
2. applied a medicinal eye drop (Latanoprost)
3. utilized both treatments

The test lasted a sum of 24 weeks and yielded the following results :

• The Mirtogenol group lowered their intraocular pressure (IOP) from 38.1 to 29 mmHg or 24%.
• The Latanoprost patients found an IOP reduction from 37.7 to 27.2 mmHg or 28%.
• The combination group began with an IOP of 38 mmHg and ended with an IOP of 23 mmHg – a 40%
• Healthy or normal eye pressure should range between about 10 to 21 mmHg.

In ending, the authors reported that, “ The combination of both was more effective for lowering IOP and the combination yielded better retinal blood flow. No serious side effects occurred during the analyze, apart from standard slope effects in patients related to Latanoprost ”. According to the National Institutes of Health, Latanoprost may cause the following adverse reactions in some users : dry eyes, eye coloring material changes, irritation and inflammation of the eyelids .
Researchers : Robert D Steigerwalt, Jr, Gianni Belcaro, Paolo Morazzoni, Ezio Bombardelli, Carolina Burki, and Frank Schonlau
Published : Mirtogenol potentiates latanoprost in lowering intraocular coerce and improves ocular blood flow in asymptomatic subjects, Clinical Ophthalmology, 2010 .
2008
A 2008 italian study tested thirty-eight subjects with exalted pressures. 20 were treated with bilberry and french maritime pine bark, the lie were given nothing. ocular acuteness, IOP, and ocular lineage flow were measured after 2, 3 and 6 months. After two months the think of IOP decreased. No side effects were observed and ocular lineage hang improved .
An better eyepiece blood stream may contribute to the prevention of glaucoma .
The researchers besides looked at the arteries of the eyes with color Doppler imagination and saw better flood hang in the subjects receiving the treatment. This suggests that fluids in the eye were being restored.

One of the researchers, Steigerwalt, said, “ Our sketch is the first demonstration showing that dietary intervention can help to control IOP and increase eyepiece blood stream in asymptomatic subjects and if taken in time, may prevent an development to higher press and diagnostic glaucoma. ”
Published : molecular sight 2008 ; 14:1288-1292, ” Effects of Mirtogenol on ocular lineage menstruation and intraocular high blood pressure in asymptomatic subjects ”
reference : Authors : Robert Steigerwalt Jr, Belcaro Gianni, Morazzoni Paolo, Ezio Bombardelli,2 Carolina Burki, Frank Schonlau, University of Chieti-Pescara in San Valentino, Italy